Events Calendar
Please note: These meetings are for the members of Broad Institute and its affiliates.
|
Calendar Options |
|
Meetings for the dates July 21, 2008 - August 01, 2008
Tuesday, July 22, 2008
|
9:30 am-11:00 am
7 Cambridge Center Monadnock Room (NE30-2040) |
Cancer Program Meeting Organized by Todd Golub "NO MEETING" |
Details |
Wednesday, July 23, 2008
|
6:00 pm-7:00 pm
7 Cambridge Center Auditorium (NE30-1154) |
Midsummer Nights Organized by Communications "The Achilles' Heels of Cancer" By accumulating changes in their DNA, cancer cells are able to grow without restraint and are often able to outsmart treatments. Yet hidden behind this apparent resilience are critical genetic weaknesses. Bill Hahn will describe how researchers are applying genomic tools to search for these "Achilles' Heels" of cancer cells, with the hope of finding new ways to diagnose and treat different types of cancers. |
Details |
Thursday, July 24, 2008
|
9:30 am-11:00 am
7 Cambridge Center Monadnock Room (NE30-2040) |
Medical and Population Genetics Organized by David Altshuler "Update on Medical Sequencing: 1000 Genomes and calling SNPs from targeted resequencing" |
Details |
Tuesday, July 29, 2008
|
9:30 am-11:00 am
7 Cambridge Center Monadnock Room (NE30-2040) |
Cancer Program Meeting Organized by Todd Golub "Synthetic lethals and cancer" |
Details |
Wednesday, July 30, 2008
|
9:30 am-11:30 am
7 Cambridge Center Monadnock Room (NE30-2040) |
Computational Biology and Bioinformatics SPECIAL SESSION Organized by Jill Mesirov and Aviv Regev "Ab initio construction of a Eukaryotic Transcriptome by Massively Parallel mRNA Sequencing" Defining the transcriptome, the repertoire of transcribed regions encoded in the genome, is a challenging experimental task. Current approaches, relying on sequencing of expressed sequence tags (ESTs) or cDNA libraries, are expensive and labor-intensive. Consequently, we know little about the transcriptome of most sequenced species. Advances in massively parallel sequencing can revolutionize the study of transcriptomes. Here, we present a novel approach for ab initio discovery of the complete transcriptome of the budding yeast, based only on the (unannotated) genome sequence and millions of short reads from a single sequencing run. Using novel algorithms, we automatically construct a highly accurate transcript catalogue, including most known transcripts, and adding 160 novel transcripts and 25 introns. Our results demonstrate that massive parallel sequencing provides accurate definition of a eukaryotic transcriptome without any prior knowledge. This framework can be applied to poorly understood organisms, for which only the genomic sequence is known. |
Details |
|
6:00 pm-7:00 pm
7 Cambridge Center Auditorium (NE30-1154) |
Midsummer Nights
"A Race Against Resistance" At every turn, it seems there is another report of dangerous bacteria outwitting the antibiotics designed to kill them. Scientists have been racing to find new antibiotics but alarmingly, progress has been slow, with few new antibiotic classes discovered in the past forty years. Deb Hung will describe how new genomic technologies may enable the discovery of new antimicrobial therapies, thereby helping to turn the tide against drug-resistant bacteria. |
Details |
Thursday, July 31, 2008
|
9:30 am-11:00 am
7 Cambridge Center Monadnock Room (NE30-2040) |
Medical and Population Genetics Organized by David Altshuler "Genetics of Schizophrenia and Bipolar Disorder" Moderator: Ed Scolnick |
Details |