Laurie Glimcher

Laurie Glimcher is the Irene Heinz Given professor of immunology in the department of immunology and infectious diseases at Harvard School of Public Health, a professor of medicine at Harvard Medical School and an associate member at the Broad Institute. Her laboratory uses biochemical and genetic approaches to elucidate the molecular pathways that regulate CD4 T helper cell development and activation. The complex regulatory pathways governing T helper cell responses are critical for both the development of protective immunity and for the abnormal immune responses underlying autoimmune diseases. With the discovery of a transcription factor, XBP-1 that controls plasma cell differentiation and the unfolded protein response, her group also studies lymphocyte commitment to the B cell lineage. Most recently, her laboratory has identified new proteins that control osteoblast commitment and activation.

Learn more about research in the Glimcher laboratory here.